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A Two-Drug Tandem & Its Relation To Brain Tumors

By : better
On : 11:23
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By Robbie Sutter


Brain tumors can be helped with the implementation of certain drugs but what does this entail, one has to wonder? It's apparent that there are drugs which have been utilized to help separate conditions in the past but I'd like to think that there are those which are entirely unique. Whatever the case may be, there is potential to consider with the results that they can bring to the surface. Is it possible that further results can come about because of a particular two-drug tandem?

YottaFire posted an article that spoke about a combination of drugs that could come into play in order to help stop the rate at which brain tumors progress. A study that was done featured a group of mice that was afflicted with the condition. With the usage of the drug tandem, it was found that their survival rates were made much better. This is reason enough why the study is worthy of the attention of organizations like Voices against Brain Cancer but what are the specifics behind it?

Dana-Farber Cancer Institute put together the study and it was determined that a combination of two drugs working together could play positively into the actions of glioblastoma. With this particular tandem, it would be able to focus on two cell signaling pathways. A previous study was done but it was deemed unsuccessful because of how only one pathway was focused on. While this improvement is worthy of note, what is more worthy has got to be a certain abnormality that is typical amongst one-third of glioblastoma patients.

It seems as though these patients lack a particular gene that has been given the name of PTEN. The gene in question works as a tumor suppressant, which is vital when considering what can happen without it. If PTEN is not present, the body undergoes a chain reaction that includes overactive molecular growth. What his means is that cells can grow to tremendous rates, which could also play into how they are able to reach the brain. The gene cannot be replaced through these drugs but this level of progression can be halted.

With this in mind, it is important to make note of all of the occurrences that can be seen in the human body. Not all of them are going to make sense but it's apparent that they work together in order to create order. When a single element is out of place, though, the risk for contracting a condition can increase; this was proven by the potential lack of the PTEN gene. With certain drugs coming together and then going on to become implemented, though, the research focused on brain tumors can be given more essential information.




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